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论文题目: Human Body Burden and Dietary Methylmercury Intake: The Relationship in a Rice-Consuming Population
全部作者: Li, Ping; Feng, Xinbin; Chan, Hing-Man; Zhang, Xiaofeng; Du, Buyun
第一作者: LI Ping
联系作者: FENG Xinbin
刊物名称: ENVIRONMENTAL SCIENCE & TECHNOLOGY
发表年度: 2015
卷: 49
期: 16
页码: 9682-9689
摘要: Rice can be the main route of methylmercury (MeHg) exposure for rice-consuming populations living in area where mercury (Hg) is mined. However, the current risk assessment paradigm for MeHg exposure is based on epidemiological data collected from fish-consuming populations. This study was designed to evaluate the relationship between dietary MeHg intake and human body burden in a rice -consuming population from the Wanshan Hg mining area in China. Hair MeHg concentrations averaged 2.07 +/- 1.79 mu g/g, and the average blood MeHg concentration across the study area ranged from 2.20 to 9.36 mu g/L. MeHg constituted 52.8 +/- 17.5% and 71.7 +/- 18.2% of total Hg (THg) on average in blood and hair samples, respectively. Blood and hair MeHg concentrations, rather than THg, can be used as a proxy of human MeHg exposure. Hair MeHg levels showed no significant monthly variation; however, hair THg can be impacted by inorganic Hg exposure. The toxicokinetic model of MeHg exposure based on fish consumption underestimated the human hair MeHg levels, and this may be a consequence of the high hair-to-blood MeHg ratio (361 +/- 105) in the studied rice-consuming population. The use of risk assessment models based on fish consumption may not be appropriate for inland mining areas where rice is the staple food.
论文链接: http://pubs.acs.org/doi/abs/10.1021/acs.est.5b00195